Holarrhena antidysenterica (Kutaja) Bark
1. WHOLE-HERB SYNERGY WITH CLEAN LABEL COMMITMENT
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3. PHARMACEUTICAL CLEAN ROOM PROCESSING
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From the very first touch of harvest, the journey of every herb is sacred. At our 30,000 sq. m. organic pharmaceutical cleanroom processing facility, we treat botanicals not as commodities, but as living treasures. All storage areas are maintained at optimal temperature and humidity levels to protect delicate herbal materials. Controlled airflow, strict cleanroom protocols and continuously monitored environments ensure freshness and quality remain intact from arrival to dispatch. All our operations run on SAP systems and are supported by Organic, FFL, GMP, FSSC 22000, FSMA, ISO 14001, ISO 45001 and several other accreditations and certifications.
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DESCRIPTION
Plant Profile
Kutaja, or Holarrhena antidysenterica, is a small to medium-sized deciduous tree. It belongs to the Apocynaceae family and grows 9 to 13 meters tall. The tree is characterized by its greyish-brown, rough, and longitudinally fissured stem bark. Its leaves are simple, opposite, and broadly ovate to elliptic, typically measuring 10–20 cm in length. The plant has fragrant white flowers in terminal corymbose cymes. It is followed by fruit in the form of paired, slender, cylindrical follicles. These follicles hold numerous light-brown, linear seeds known as Indrayava. The bark is the most valued part for medicine. It is thin and tastes bitter. It possesses a ""buff"" to rust-brown inner surface. This surface is used extensively in Ayurvedic formulations for gastrointestinal ailments. Holarrhena antidysenterica mainly grows in the Indian Subcontinent. It is also found in many tropical and subtropical areas of Asia. In India, it grows widely across the country. It grows in deciduous forests, open wastelands, and the sub-Himalayan region. You can see it at altitudes up to 1,300 meters. It is especially common in the mountains and dry forests of states like Uttar Pradesh, Assam, Bihar, Odisha, and Andhra Pradesh.
Healthcare Perspective
In traditional healthcare systems, the bark of Kutaja (Holarrhena antidysenterica) is highly regarded for its multifaceted therapeutic potential. In Ayurveda, this herb is a top Grahi (absorbent) and Stambhana (astringent). It mainly helps with gastrointestinal issues like Atisara (diarrhea) and Pravahika (dysentery). It is believed to balance the Kapha and Pitta doshas. In Siddha and other ethnobotanical practices, the bark is used as decoctions or powders. It helps with many issues, like malarial fevers, skin diseases, internal parasites, and bleeding piles. Modern studies confirm traditional uses by highlighting steroidal alkaloids like conessine. These compounds are known for their antimicrobial effects and ability to regulate gut motility. Additionally, they lack the common side effects of synthetic emetics.
Phytochemical Composition
Kutaja (Holarrhena antidysenterica) has a strong chemical profile. It contains steroidal alkaloids, making up about 1.5% to 4.2% of the dry weight of the stem bark. The most prominent and clinically significant alkaloid is conessine. It serves as the primary marker for the plant’s therapeutic efficacy in managing intestinal disorders. Other major alkaloids isolated from the bark include isoconessine, kurchine, conessidine, holarrhimine, and conimine. The bark has more than just alkaloids. It also contains various non-alkaloidal compounds. These include tannins, which make it astringent. Triterpenoids include lupeol and betulinic acid. There are also flavonoids, saponins, and phenolic acids. Additionally, a unique digitenol glycoside known as holadysone has been identified. Various resins and gums that collectively support the plant's biological activity."
Precautions
Do not use if you have abdominal pain or diarrhea. Consult a healthcare professional before use if you are pregnant, nursing, or taking any medications. Discontinue use if diarrhea or loose stools occur. Do not exceed the recommended dose. Not intended for long-term use.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.*
Available Forms
Holarrhena antidysenterica (Kutaja) Bark C&S
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Holarrhena antidysenterica (Kutaja) Bark Powder
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